Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History

Adai Technology

Status: Completed

Conditions: Addiction, Substance

Treatments: Behavioral: Static Approach Bias Modification; Behavioral: Adaptive Approach Bias Modification

Study type: Interventional

Funder types: Other

Identifiers

NCT05794438

TS001

Details and patient eligibility

About

A randomized controlled trial will be conducted to investigate whether a proposed algorithm that adjusts the congruency ratio based on the user's performance and difficulty can enhance the effectiveness of approach bias modification. Methamphetamine users will be recruited and randomized into an algorithm group, a standard group, and a control group.

Full description

To assess the efficacy of an adaptive approach bias modification (A-ApBM) paradigm with gamified designs and dynamic difficulty adjustments in reducing cue-induced craving in individuals with methamphetamine use history. DESIGN: Randomized controlled trial with three study groups: Adaptive ApBM (A-ApBM), Static ApBM (S-ApBM), and control. A-ApBM and S-ApBM groups engaged in ApBM training using a smartphone application for four weeks. A-ApBM used an adaptive algorithm to dynamically adjust the difficulty level based on individual performance, while S-ApBM had a static difficulty level. Cue-induced craving scores were assessed using a visual analog scale at baseline, post-intervention, and at week-16 follow-up.

Enrollment: 139 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• having a history of methamphetamine use of at least one year

Exclusion criteria

• could not fluently operate an Android or an iOS smartphone
• having mental health conditions other than MUD

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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139 participants in 3 patient groups

Adaptive Approach Bias Modification

Experimental group

Treatment:

Behavioral: Adaptive Approach Bias Modification

Static Approach Bias Modification

Experimental group

Treatment:

Behavioral: Static Approach Bias Modification

Control

No Intervention group