Gamma Knife Radiosurgery on Tectal Plate Gliomas

Al-Azhar University

Status: Completed

Conditions: Gamma Knife Radiosurgery; Tectal Plate Gliomas

Treatments: Procedure: Gamma Knife Radiosurgery

Study type: Observational

Funder types: Other

Identifiers

NCT07015710

DFM-IRB 00012367-25-05-007

Details and patient eligibility

About

This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).

Full description

Tectal plate gliomas (TPGs) represent a subset of brainstem gliomas that are predominantly slow-growing, low-grade tumors and rarely produce neurological deficits.

Viable options include biopsy and monitoring with serial neuroimaging, surgical resection, radiotherapy (either early following surgery or late on evidence of disease progression), chemotherapy, and stereotactic radiosurgery (SRS).

SRS using Gamma Knife radiosurgery (GKRS) has been identified in small case series as a safe and promising approach for managing TPGs that necessitate intervention beyond mere observation.

Enrollment: 60 patients

Sex: All

Ages: 5 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age from 5 to 55 years.
• Both sexes.
• Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Exclusion criteria

• High-grade glioma.
• Tumor extension beyond the tectal region.

Trial design

60 participants in 1 patient group

Tectal Plate Gliomas group

Description:

Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Treatment:

Procedure: Gamma Knife Radiosurgery