Gammaglobulins Level is Predictive Factor of Evolution in Sarcoidosis (GAMES)

Rennes University Hospital

Status: Completed

Conditions: Sarcoidosis

Treatments: Biological: Analysis of gamma globulin

Study type: Observational

Funder types: Other

Identifiers

NCT03259282

35RC16_3046_GAMES

Details and patient eligibility

About

Evaluation of the rate of achievement of serum protein electrophoresis (PPE) in diagnosis in a retrospective cohort of patients at Rennes University Hospital

Full description

In 50% of cases, sarcoidosis is associated with polyclonal hypergammaglobulinemia. The other forms have a normal gamma globulin level.

The level of gamma globulinemia has not yet been studied as an evolutionary predictive factor. Furthermore, there are disseminated granulomatoses sharing common characteristics with sarcoidosis, associated with Common Variable Immunodeficiency deficit (DICV) type Primary Immunodeficiency syndrome (DIP), thus occurring in hypogammaglobulinemic patients.

Enrollment: 78 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients newly diagnosed with sarcoidosis

Exclusion criteria

• Comorbidity responsible for a change in the level of gamma globulin
• Other etiology of granulomatosis