Garlic With Lime Juice and Chlorhexidine Mouthwash (mouthwash)

Cairo University (CU)

Status: Unknown

Conditions: Gingival Bleeding

Treatments: Drug: chlorhexidine; Drug: garlic with lime mouth wash

Study type: Interventional

Funder types: Other

Identifiers

NCT03105960

151087 (Registry Identifier)

Details and patient eligibility

About

the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.

Full description

the study about herbal mouth wash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and show their effect on gingival bleeding and strepococcus bacteria present in saliva and plaque.

1. Preparation of garlic with lime juice will occur under aseptic condition.and give it to the first group.

   provide chlorhexidine to the second group.

2. Collection of plaque and saliva samples will be obtained from children who fulfilled the inclusion criteria.

3. Asses gingival condition by asking patient.

4. Subjects will be instructed to rinse for 14 days, twice daily.

5. Morning after breakfast and night before going to bed.

6. With 10 ml (undiluted) of the assigned mouthwash for 30 s and then expectorate the rinse.

7. Again after 14 days, the saliva and plaque samples will be taken and inoculated on blood agar plates to determine the colony count and the gingival index by loe and illness will be assessed.

Enrollment: 36 estimated patients

Sex: All

Ages: 9 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Children aged between 9 and 12 years.
2. Children are having normal occlusion (no crowding), non-compromised oral health (brushed their teeth once-daily) using toothbrush and non-fluoridated toothpaste. And practicing no other oral hygiene measures.
3. Medically free history.
4. Absence of orthodontic appliances.

Exclusion criteria

1. History of current or recent (at least for the past 1 month) antibiotic usage or other medications.
2. Presence of Abscess, draining sinus, cellulitis, or other conditions requiring emergency dental treatment.
3. not willing to comply with the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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36 participants in 2 patient groups

garlic with lime juice mouthwash

Experimental group

Description:

garlic with lime juice mouthwash is herbal antimicrobial .children were instructed to rinse for 14 days, twice daily, ,10 ml (undiluted) for 30 second and then expectorate . To prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.

Treatment:

Drug: garlic with lime mouth wash

chlorhexidine mouthwash

Active Comparator group

Description:

chlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days. it is commercial mouthwash .

Treatment:

Drug: chlorhexidine