Gastric Bacterial Colonization of Preterm Neonates

Christiana Care Health Services

Status: Completed

Conditions: Microbial Colonization; Preterm Birth

Treatments: Other: Observational

Study type: Observational

Funder types: Other

Identifiers

NCT05385939

Christiana Care Health System

Details and patient eligibility

About

This prospective cohort study was conducted in the Christiana Care Health System Neonatal Intensive Care Unit. It occurred at two time periods: Time period 1 included infants admitted to the traditional, open bay NICU. Time period 2 included infants admitted to the new private, single family room NICU. There was a 3 month period between Time period 1 and Time period 2 to ensure that there was no patient overlap. Stool samples and environmental samples were collected at 1 and 4 weeks after birth in both time periods. The objective of this study was to establish the gastrointestinal microbiome of infants born at less than 32 weeks gestation admitted to the exiting open bay NICU and compare it to the gastrointestinal microbiome of infants born at less than 32 weeks admitted to the new private, single family room NICU.

Enrollment: 122 patients

Sex: All

Ages: 1 week to 6 months old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Less than 32 weeks gestation at birth

Exclusion criteria

• Infants in Time period 2 that were admitted to the traditional, open bay NICU

Trial design

122 participants in 2 patient groups

Time period 1

Description:

Time period one included infants admitted to the current traditional, open bay NICU.

Treatment:

Other: Observational

Time period 2

Description:

Time period 2 included infants admitted to the private, single family room NICU.

Treatment:

Other: Observational