Gastric Emptying of Rice With Different Starch Properties

Purdue University

Status: Completed

Conditions: Appetitive Behavior

Treatments: Other: Brown rice, low amylose; Other: White rice, slow; Other: Brown rice, high amylose; Other: White rice, low amylose; Other: White rice, high amylose; Other: White rice, resistant; Other: Fructooligosaccharide (FOS)

Study type: Interventional

Funder types: Other

Identifiers

NCT03035981

1405014904

Details and patient eligibility

About

Glycemic carbohydrates are associated with metabolic disturbances, such as type II diabetes, due to rapid digestion of starch into glucose. The specific properties of starch within these foods has been studied for the purpose of slowing their digestion rate and improving related physiological outcomes, such as gastric emptying rate. The current study investigated the relationship among starch digestion, gastric emptying rate and satiety in white and brown rice.

Full description

Studies have indicated that starch-based foods with somewhat high amylose content have slower in vitro starch digestion rates, which relate to a low glycemic response. Low glycemic response is associated with delayed gastric emptying rate as well. Therefore, we hypothesized that rice with a slow starch digesting property would delay gastric emptying. White and brown rice with varying amylose contents were used in this study. A 13C-labeled octanoic acid breath test method was used to measure gastric emptying rate, and questionnaires were used to assess hunger and fullness during the testing sessions. Twelve healthy volunteers were recruited to participate in a crossover design study with six rice treatments and outcome measurements were gastric emptying and satiety assessments. One fermentable carbohydrate (fructooligosaccharide, FOS) solution was used to validate the production of breath hydrogen.

Enrollment: 12 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal body mass index (18 kg/m2 ≤ BMI ≤ 25 kg/m2)

Exclusion criteria

• Under any medication
• History of any gastrointestinal disease or surgery
• Diabetes
• Smoker

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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12 participants in 7 patient groups

White rice, low amylose

Experimental group

Description:

Cooked white rice with low amylose content

Treatment:

Other: White rice, low amylose

White rice, high amylose

Experimental group

Description:

Cooked white rice with high amylose content

Treatment:

Other: White rice, high amylose

White rice, slow

Experimental group

Description:

Cooked white rice with slow digesting starch

Treatment:

Other: White rice, slow

White rice, resistant

Experimental group

Description:

Cooked white rice with resistant starch

Treatment:

Other: White rice, resistant

Brown rice, low amylose

Experimental group

Description:

Cooked brown rice with low amylose content

Treatment:

Other: Brown rice, low amylose

Brown rice, high amylose

Experimental group

Description:

Cooked brown rice with high amylose content

Treatment:

Other: Brown rice, high amylose

Fructooligosaccharide (FOS)

Experimental group

Description:

Fermentable carbohydrate solution

Treatment:

Other: Fructooligosaccharide (FOS)