Gastric Volume After Ingestion of Carbohydrate Drink vs Water in Obese Volunteers

Prince of Songkla University

Status: Active, not recruiting

Conditions: Gastric Emptying; Obesity

Treatments: Procedure: Preopertive drink

Study type: Interventional

Funder types: Other

Identifiers

NCT05827029

REC.65-236-8-1

Details and patient eligibility

About

This randomized crossover study compares gastric residual volume after ingestion of carbohydrate drinks and water in obese volunteers. The main question[s] it aims to answer are:

• Is it safe for obese patients to shorten their fasting by allowing preoperative drinks?
• How long is the gastric emptying time in obese patients? Participants also will be evaluated the level of thirst/hungry and blood sugar.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteers
• Age 18 - 65 years old
• BMI ≥ 30 kg/m2
• NPO for at least 6 hours before the study

Exclusion criteria

• Diabetes Mellitus
• Chronic kidney disease or End-stage renal disease
• Use of any medication that affects gastric secretion or emptying (Histamine 2 receptor antagonist eg. Ranitidine/Proton pump inhibitor eg. Omeprazole/Acid neutralization eg. Aluminium hydroxide/Prokinetic eg. Domperidone) within the past 24 hours
• Gastroesophageal reflux disease
• Pregnancy
• History of upper gastrointestinal surgery
• In diet program or use appetite suppressant drug (eg. Liraglutide, Naltrexone, Phentermine, Diethylpropion) within the past 24 hours

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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30 participants in 2 patient groups, including a placebo group

Preoperative carbohydrate drink

Experimental group

Treatment:

Procedure: Preopertive drink

Water

Placebo Comparator group

Treatment:

Procedure: Preopertive drink