Gastrointestinal Microcirculation During Cardiopulmonary Bypass

Johann Wolfgang Goethe University Hospital

Status: Completed

Conditions: Tree Number E04.100.376; Tree Number E04.928.220; MeSH Heading Cardiac Surgical Procedures

Treatments: Procedure: Heart Lung machine

Study type: Observational

Funder types: Other

Identifiers

NCT01425931

O2C-001AHK

Details and patient eligibility

About

O2C is a diagnostic device for non-invasive determination of oxygen supply in microcirculation of blood perfused tissues. The optical sensor is easy to handle and guarantees reproducible examinations of local oxygen supply of tissues in clinics as well as in research. The examinations are without any strain for your patient.

Determines by use of a glass fibre probe:

Blood Flow in Microcirculation Capillary-Venous Oxygen Saturation Blood Filling of Microvessels Blood Flow Velocity This device makes it possible to supervise the local oxygen supply of organs and tissue.

With it is possible to measure locally the amount of oxygen which is transported into the region of interest and to diagnose local oxygen consumption of an organ. O2C's novelty is monitoring the energetic metabolism of cells by measuring the oxygen uptake with an optical sensor probe. Pathological O2-supply, which can lead to angiogenesis or cell-death and subsequently to organ failure, now can be detected in an early state by use of the new sensor system.

One of these new developed sensors are used to place in rectal position during extracorporeal circulation to determine the microcirculation.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients on extracorporeal circulation

Exclusion criteria

• Haemorrhoidal lesions

Trial design

50 participants in 1 patient group

Extracorporeal circulation

Description:

all patients were measured by microcirculation device O2C

Treatment:

Procedure: Heart Lung machine