Gastrointestinal Microflora and Serum Metabolomics in Patients With Pancreatic Cancer and Chronic Pancreatitis

Naval Military Medical University

Status: Enrolling

Conditions: Chronic Pancreatitis; Pancreatic Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT06411470

CHEC2024-149

Details and patient eligibility

About

The investigators plan to collect throat swabs, saliva, feces and serum samples from pancreatic cancer patients, chronic pancreatitis patients and healthy people and clarify the characteristics of oral flora and serum metabolome of pancreatic cancer patients.

Enrollment: 600 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1.Pathologic diagnosis of pancreatic ductal adenocarcinoma；Diagnosis of CP defined as having obvious morphological features of CP (i.e., the presence of pancreatic calcifications on CT scan and/or magnetic resonance cholangiopancreatography)；Other benign disease populations without pancreatic lesions.

Exclusion criteria

1. Pregnant women.
2. Patients with coagulation disorders who are unable to undergo blood tests.
3. Have a history of using antibiotics or probiotics within the past 3 months.

Trial design

600 participants in 3 patient groups

pancreatic cancer

Description:

Pathologic diagnosis of pancreatic ductal adenocarcinoma

chronic pancreatitis

Description:

Diagnosis of CP defined as having obvious morphological features of CP (i.e., the presence of pancreatic calcifications on CT scan and/or magnetic resonance cholangiopancreatography)

healthy people

Description:

Other benign disease populations without pancreatic lesions