Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury

University of Aarhus

Status: Completed

Conditions: Brain Injury; Constipation

Study type: Observational

Funder types: Other

Identifiers

NCT02428790

ABITransitTimeHammel

Details and patient eligibility

About

Empirically patients with acquired brain injury (ABI) are often constipated. This is a major clinical issue. Nevertheless, this has only been sparsely studied.

The investigators will measure gastrointestinal transit time (GITT) in 30 patients with ABI, and compare this to healthy controls. Secondly heart rate variability (HRV) is measured in these patients, and associations between HRV and GITT are investigated.

Enrollment: 25 patients

Sex: All

Ages: 18 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ABI:
• Moderate to severe traumatic brain injury (TBI) (Glasgow Coma Scale (GCS) score 3-12 at admission)
• or Stroke
• or Anoxic brain injury
• Ability to swallow the capsules used to assess GITT
• Ability to give meaningful informed consent to participate in the study

Exclusion criteria

• Major abdominal disorders
• Severe acute comorbidity
• Known cancer
• Pregnancy
• Known autonomic neuropathy
• Other known neurological disorder

Trial design

25 participants in 1 patient group

ABI Patients

Description:

Patients with acquired brain injury.