Gaze Contingent Feedback in Major Depressive Disorder (MDD)

Tel Aviv University

Status: Completed

Conditions: Depression, Unipolar; Depressive Disorder, Major; Depressive Disorder

Treatments: Behavioral: Attention Modification

Study type: Interventional

Funder types: Other

Identifiers

NCT02945735

TAUDEPI

Details and patient eligibility

About

The purpose of this study is to determine whether giving gaze-contingent feedback is an effective attention modification procedure, helping in the treatment of Major Depressive Disorder (MDD)

Full description

The study examines giving depressive participants gaze-contingent feedback as a novel attention training procedure. Half of the participants will receive contingent feedback while the other half would receive non-contingent "placebo" feedback.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A signed consent form
• Men and women between the ages of 18 and 65.
• Meeting a current diagnosis of Major Depressive Disorder (MDD) according to the DSM-IV
• MDD as the primary diagnosis: In cases of co-morbidity, MDD will be deemed as the most distressing and clinically significant condition among the co-morbid disorders
• Stable pharmaco-therapy: Participants receiving a pharmacological treatment who are taking a stable medication for at least 3 months before the beginning of the procedure.

Exclusion criteria

• Psychotic episode in the past or the present time.
• Co-morbidity with any neurological disorder (i.e., epilepsy, brain injury).
• Another psychotherapeutic treatment during the study.
• Usage of neuroleptic medication.
• Change in medication status during the study.
• Substantial usage of drugs or alcohol in the present time.
• Poor judgment capacity (i.e., children under 18 and special populations).
• High Risk of Suicide.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

gaze-contingent

Experimental group

Description:

Attention modification: participants will receive gaze-contingent feedback according to their viewing patterns

Treatment:

Behavioral: Attention Modification

non-gaze contingent

Placebo Comparator group

Description:

Participants will receive non-gaze-continent feedback unrelated to their viewing patterns

Treatment:

Behavioral: Attention Modification