GDM Post Partum Screening

Pediatrix

Status: Terminated

Conditions: Gestational Diabetes; Diabetes; Diabetes Mellitus, Type 2

Treatments: Diagnostic Test: 2 hour glucose tolerance test using 75g glucose drink

Study type: Observational

Funder types: Other

Identifiers

NCT03946631

GDM 2019 iris 01-18-0028

Details and patient eligibility

About

Immediate postpartum screening for diabetes mellitus in women with gestational diabetes

The objective of this study is to determine if screening for type 2 diabetes can be done 24 hours after delivery, versus 6-12 weeks postpartum, in recently delivered women having been diagnosed with gestational diabetes requiring medication therapy in the antecedent pregnancy.

Full description

1 Overview The purpose of the project is to determine if screening for diabetes mellitus, in women with gestational diabetes, can be done 24 hours postpartum versus 6-12 weeks postpartum.

Primary Objective: To compare the results from screening for type 2 diabetes 24 hours postpartum versus 6-12 weeks postpartum.

Design and Project Type Prospective cohort study. Women diagnosed with gestational diabetes and receiving anti-hyperglycemic medication therapy will have testing for type 2 DM done 24 hours after delivery. They will also have routine screening for type 2 DM done at 6-12 weeks postpartum.

Description of Intervention The intervention is early screening for type 2 DM which involves oral intake of a 75-- gram (g) glucose drink and subsequent measurement of fasting, 1- hour, and 2- hour postprandial point of care fingerstick s for blood glucose measurement.

Instruments Fingerstick testing will be done with StatStrip Glucose Hospital Meter (Nova Biomedical). This device is used routinely throughout the hospital and has been validated for use in all patients, including the critically ill. Using point of care testing will allow for accurate results with less pain for the patient, as compared to (fingerstick versus venipuncture).

Enrollment: 21 patients

Sex: Female

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant, or recently postpartum, women with the diagnosis of GDM requiring medication therapy after 20 weeks,
• >18 years-old (yo)yo,
• English speaking.

Exclusion criteria

• have pre-existing type 2 DM,
• did not require anti-hyperglycemic medication therapy (GDMA1),
• early onset GDM (<20 weeks).
• do not speak English .

Trial design

21 participants in 1 patient group

Blood Glucose Test - 2hour GTT

Description:

Only one arm: intervention group. The intervention is fasting 2 hour glucose tolerance test in the immediate postpartum period. The screening test consists of fingerstick blood glucose testing after a glucose drink. First, a fasting blood glucose finger stick will be performed. Second, the glucose drink is orally ingested containing 75g glucose. The drink is to be orally ingested over 60 seconds. Lastly, fingerstick blood glucose testing is completed at 1 hour post drink and 2 hours post drink.

Treatment:

Diagnostic Test: 2 hour glucose tolerance test using 75g glucose drink