Gender-specific aEEGs and Outcome in Preterms

Medical University of Vienna

Status: Completed

Conditions: Gender Role Disorder, Male to Female Type

Study type: Observational

Funder types: Other

Identifiers

NCT01562236

gender148

Details and patient eligibility

About

Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography (aEEG) and to correlate these findings with neurodevelopmental outcome.

Methods: Preterm infants born <30 weeks' gestational age between 2000 and 2002 were prospectively included. aEEGs obtained within the first two weeks of life were evaluated and classified according to background activity, sleep-wake cycling (SWC) and seizure activity. Outcome was assessed at three years.

Enrollment: 148 patients

Sex: All

Ages: 24 to 30 weeks old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• born<30 weeks gestational age
• who had aEEGs in first 2 weeks of life
• who were assessed for outcome at 3 years of age

Exclusion criteria

• born>30 weeks gestational age
• had no aEEGs in first 2 weeks of life
• lost for follow-up at 3 years