Gender-specific Associations Between Quality of Life and Leukocyte Telomere Length

Jung-Ha Kim

Status: Completed

Conditions: Apparently Healthy People Aged 55 and Over

Treatments: Other: quality of life

Study type: Observational

Funder types: Other

Identifiers

NCT03151824

C 2013152(1112)

Details and patient eligibility

About

Quality of life (QoL) is an important factor for successful aging. Telomere length is an indicator of cellular aging and cumulative biological stress and is thus related to health status and survival. However, the relationship between QoL and telomere length has not yet been examined. In this study we investigated the relationship between leukocyte telomere length (LTL) and QoL.

However, the relationship between overall QoL and LTL has not previously been investigated. Therefore, this study was conducted to examine the relationship between LTL and QoL. QoL was measured by the Korean version of the 36-item short-form health survey (SF-36), which is a multidimensional scale consisting of subjective evaluation.

Enrollment: 164 patients

Sex: All

Ages: 55+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• married couple
• apparently healthy subjects above 55 years

Exclusion criteria

• Subjects who had experienced hormone therapy
• Subjects who had been diagnosed with dementia, Parkinson's disease, stroke, ischemic heart disease, congestive heart failure, arrhythmia, depression, cancer, thyroid disorders, or chronic renal disease