Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women

University of Aarhus

Status: Completed

Conditions: Infertility

Treatments: Procedure: endometrial biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT02219425

Miacol-2014-2H

Details and patient eligibility

About

The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.

Full description

An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7.

Tissue is analysed and compared for changes in gene expression profile using Seq RNA

Enrollment: 10 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Fertile women
• Age: 18-40 years
• BMI: 18-32
• Regular menstrual cycle
• No use of hormonal contraceptives or IUD the last 3 months

Exclusion criteria

• Patients in need of a interpreter
• Suspected intrauterine abnormalities
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

10 participants in 1 patient group

endometrial biopsy

Other group

Treatment:

Procedure: endometrial biopsy