Gene Expression in Patients With Epiretinal Membranes

Medical University of Silesia

Status: Unknown

Conditions: Proliferative Diabetic Retinopathy

Study type: Observational

Funder types: Other

Identifiers

NCT01946451

SilesianMU

Details and patient eligibility

About

The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Caucasian race,
• both males and females,
• aged ≥ 55 years,
• suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR).
• Presence of ERM was proven in optical coherence tomography (OCT) examination.

Exclusion criteria

• aged < 55 years,
• systemic connective tissue disease,
• active inflammatory process

Trial design

0 participants in 2 patient groups

Idiophatic ERMs

Secondary ERMs