Gene Polymorphism of Taste Receptors and Circulating Endocannabinoids in Normal Weight and Obese Subjects

University of Cagliari

Status: Completed

Conditions: Nutritional Physiological Phenomena

Study type: Observational

Funder types: Other

Identifiers

NCT02729584

Cagliari

Details and patient eligibility

About

The study aims at evaluating in normal weight and obese subjects those factors such as taste sensitivity and circulating endocannabinoids in influencing dietary choice and thereby lipid and energy metabolism in order to design personalized nutritional strategies.

Enrollment: 110 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Body Mass Index (BMI), range for normal weight subjects 17.5-24.95, for obese subjects 29.6-52.20
• No intake of nutritional supplements for at least six months before the trial

Exclusion criteria

• major diseases (diabetes, kidney disease, etc.),
• pregnancy or lactation;
• food allergies;
• the use of medications that interfere with taste or smell (e.g., steroids, antihistamines, certain antidepressants).

Trial design

110 participants in 2 patient groups

Normal weight

Obese