Gene Polymorphisms and Gene Products as Biological Markers of Aging and Correlation With Clinical Geriatric Assessment, Tolerance of Chemotherapy and Outcome in Elderly Breast Cancer Patients (EBS)

Universitaire Ziekenhuizen KU Leuven

Status: Completed

Conditions: Breast Cancer; Elderly

Study type: Observational

Funder types: Other

Identifiers

NCT00849758

S51518

Details and patient eligibility

About

The goal is to study the biology of aging in breast cancer patients, and to study the impact of chemotherapy on aging related blood biomarkers.

Enrollment: 110 patients

Sex: Female

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 70 years or older
• Female
• Early breast cancer
• Candidate for systemic adjuvant therapy

Trial design

110 participants in 2 patient groups

1

Description:

chemotherapy: elderly patients receiving 4x adjuvant taxotere cyclophosphamide adjuvant for breast cancer

2

Description:

adjuvant hormone therapy: 40 patients receiving adjuvant aromatase inhibitor without chemotherapy