Genetic and Neural Factors in Alcohol-Related Cognition

Virginia Commonwealth University (VCU)

Status: Completed

Conditions: Alcohol Abuse

Treatments: Behavioral: MRI Scanner

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03725345

K01AA026647 (U.S. NIH Grant/Contract)

HM20013938

Details and patient eligibility

About

This study examines the genetic factors that impact cognitive processes and behavior after alcohol consumption. Participation in this project will contribute to a better understanding of cognitive factors that influence alcohol misuse.

Enrollment: 9 patients

Sex: All

Ages: 21 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• English speaking
• No current or regular use of prescribed or illicit psychoactive drugs
• Free of major health problems (e.g., diabetes, HIV, Parkinson's disease)
• Free of neurological or psychiatric disorders
• No current drug abuse (e.g., recreational drug use).
• Right-hand dominant
• Free of claustrophobia
• Free of pregnancy or suspected pregnancy
• Absent MRI risk factors (e.g., implanted medical device, body mass index > 35, braces)
• Free of medical conditions that render individuals with overly sensitive hearing
• Non-naive to alcohol consumption

Exclusion criteria

• Not meeting the inclusion criteria listed above

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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9 participants in 2 patient groups

Alcohol Group

Active Comparator group

Description:

Participants who have recently consumed alcohol.

Treatment:

Behavioral: MRI Scanner

No Alcohol Group

Sham Comparator group

Description:

Participants who have not recently consumed alcohol.

Treatment:

Behavioral: MRI Scanner