Genetic Assessment of the Patients With Metabolic Syndrome (GENMetS)

Medical University of Lodz

Status: Unknown

Conditions: Metabolic Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01268696

RNN/202/10/KE

Details and patient eligibility

About

Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. The exact mechanisms of the complex pathways of metabolic syndrome are not yet completely known. The pathophysiology is extremely complex and has been only partially elucidated. Most patients are older, obese, sedentary, and have a degree of insulin resistance. Stress can also be a contributing factor. The most important factors are:

weight, genetics, aging, sedentary lifestyle,excess caloric intake. In our study we will assess the role of some polymorphisms in the pathology of metabolic syndrome.

Full description

Eligibility criteria to the study:

• patients with metabolic syndrome
• with written consent

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with metabolic syndrome according to IDF,AHA and NHLBI 2009

Exclusion criteria

• diabetes type 1
• cancer
• not consent
• steroid therapy
• alcohol or drug abuse
• chronic inflammatory disease
• pregnancy or lactation
• severe hypothyroidism
• immunosuppressive treatment
• operation or severe injury during the last month

Trial design

300 participants in 2 patient groups

control group

Description:

healthy volunteers

Metabolic group

Description:

Patients with metabolic syndrome