Genetic Association of Glucocorticoid Receptor Gene Polymorphisms With Binge Eating

Corporacion Parc Tauli

Status: Completed

Conditions: Binge-Eating Disorder; Eating Disorders; Obesity; Diabetes Type 2; Adolescent Behavior

Treatments: Diagnostic Test: BED Questionnaire

Study type: Interventional

Funder types: Other

Identifiers

NCT04786054

BEDCAI37628

Details and patient eligibility

About

The aim of the present study was to specifically screen obese diabetic adolescent female individuals for BED, checking the variants of the GR gene (rs56149945; rs41423247) amongst identified individuals, and this led to assessing the impact of binge eating disorders on glycaemic control in obese diabetic adolescent females in Pakistan, South Asia.

Full description

Challenges in eating for diabetic adolescents can be categorized as eating disorders (ED) and disordered eating symptoms (DES). Binge-eating disorder (BED) is defined as recurrent episodes of binge eating at least once a week over a three-month time period and it is accompanied by feeling the lack of control and marked distress over one's eating behaviour. The aim of the present study was to specifically screen obese diabetic adolescent female individuals for BED, checking the variants of the GR gene (rs56149945; rs41423247) amongst identified individuals, and this led to assessing the impact of binge eating disorders on glycaemic control in obese diabetic adolescent females in Pakistan, South Asia.

Enrollment: 91 patients

Sex: Female

Ages: 10 to 19 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Unmarried females diagnosed with Type 2 diabetes > 12 months
• Age 10-19 years
• Obesity class I and II (based on BMI range of 30 - 40).

Exclusion criteria

• Presence of psychosis, major psychiatric or neurocognitive disorder
• Substance use
• Untreated attention-deficit hyperactivity disorder
• Use of psychopharmacological medications or psychotherapy
• Class III obesity

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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91 participants in 2 patient groups

Group BED

Active Comparator group

Description:

Those who are diagnosed with having Binge Eating disorder. These individuals qualified after the questionnaire was administered.

Treatment:

Diagnostic Test: BED Questionnaire

Group Non-BED

No Intervention group

Description:

Those who are not diagnosed with having Binge Eating disorder