Genetic Basis of Pacing-induced Cardiomyopathy

The Guthrie Clinic

Status: Completed

Conditions: Pacemaker, Artificial; Cardiomyopathies

Treatments: Other: Saliva sample

Study type: Observational

Funder types: Other

Identifiers

NCT03317964

1706-34

Details and patient eligibility

About

The purpose of this study is to collect a saliva sample from patients with a pacemaker to study genes involved in cardiomyopathy, a condition where the heart muscle is abnormal.

Full description

DNA will be extracted from the saliva to test for changes in genes related to cardiomyopathy.

Enrollment: 153 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who have been assessed for cardiomyopathy

Exclusion criteria

• Patients who do not have adequate follow up care to determine if they do or do not have cardiomyopathy

Trial design

153 participants in 2 patient groups

Saliva - cardiomyopathy

Description:

Saliva sample for genetic testing from subjects who developed cardiomyopathy

Treatment:

Other: Saliva sample

Saliva - no cardiomyopathy

Description:

Saliva sample for genetic testing from subjects who do not have cariomyopathy

Treatment:

Other: Saliva sample