Genetic Determinants of Opioids Analgesia

Hadassah Medical Center

Status: Completed

Conditions: Nephrolithiasis

Treatments: Drug: Alfentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT00226564

yc19554-HMO-CTIL

Details and patient eligibility

About

The response to opioids varies greatly among individuals. Some of these variability is accounted for by genetic factors.

The present study was designed to evaluate the possibility that genetic polymorphism in the gene encoding for mu opioid receptor may explain variability in the response to alfentanil during lithotripsy.

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 20

Exclusion criteria

• Regular use of opioid drugs
• Known hypersensitivity to alfentanil

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)