Genetic Examination of Patients With Primary Multiple Hernia

Herlev Hospital

Status: Unknown

Conditions: Multiple Hernia

Study type: Observational

Funder types: Other

Identifiers

NCT00979095

H-D-2008-126

Details and patient eligibility

About

The investigators are performing a genetic study of patients with multiple hernias (at least 3 primary hernias) versus a healthy control group. This genetic information is compared with circulating and subcutaneously biomarkers such as matrix-metalloproteinases (MMP's).

The hypothesis is that patients with multiple hernias have different expression of specific genes compared to the healthy control group.

Full description

Other examinations performed on the patients enrolled in this study:

• Ultrasound (US) examination of the abdominal aorta to discover possible abdominal aortic aneurysms.
• Beightons score to evaluate the degree of joint hypermobility.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with minimum 3 primary hernias

Exclusion criteria

• Patients under 18 years

Trial design

60 participants in 2 patient groups

Multiple hernia

Description:

Patients with more than 3 primary hernias

Control group

Description:

Patients without hernias