Genetic Factors and CP Pregnancy Outcomes

Naval Military Medical University

Status: Active, not recruiting

Conditions: Genetic Mutation; Chronic Pancreatitis; Pregnancy Related

Treatments: Diagnostic Test: genetic sequencing

Study type: Observational

Funder types: Other

Identifiers

NCT06055595

CP-gene-pregnancy outcomes

Details and patient eligibility

About

To explore the impact of chronic pancreatitis (CP) susceptibility genes on pregnancy outcomes.

Full description

The goal of this observational study is to explore the impact of CP susceptibility genes (SPINK1, PRSS1, CTRC, CFTR) on pregnancy outcomes (including both maternal and fetal outcomes) in a large Chinese cohort. Participants will be asked to provide their pregnancy-related data.

Enrollment: 160 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• female patients with a diagnosis of chronic pancreatitis
• have known genetic backgrounds and pregnancy history
• agree to join the study and provide informed consent

Exclusion criteria

• patients without documented pregnancy
• patients who denied to provide pregnancy-related information, or with incomplete pregnancy characteristics and/or outcomes
• patients with other autoimmune comorbidities that might influence pregnancy outcomes, such as systemic lupus erythematosus, autoimmune thyroid diseases, etc