Genetic Factors in Chronic Sinusitis

The University of Chicago

Status: Enrolling

Conditions: Chronic Sinusitis

Study type: Observational

Funder types: Other

Identifiers

NCT00880516

16749A

Details and patient eligibility

About

The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis.

Enrollment: 1,200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age> 18 years
• Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease.

Exclusion criteria

• Genetic or acquired immunodeficiency
• Ciliary dyskinesia
• Cystic fibrosis
• Autoimmune disease
• Cancer of the sinuses

Trial design

1,200 participants in 2 patient groups

control

Description:

Adults with normal sinuses

case

Description:

Adults with chronic sinusitis and positive findings on imaging.