Genetic Markers of Circulating Tumor DNA for Monitoring Breast Cancer Patients in Costa Rica

Universidad de Costa Rica

Status: Unknown

Conditions: Mutation, Point; Metastatic Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT04163159

B9316 (Other Identifier)

R018-SABI-00193

Details and patient eligibility

About

The use of circulating tumor DNA (ctDNA) as a noninvasive test for breast cancer monitoring throughout the course of the disease

Full description

The concentrations of the cell free DNA (cfDNA) and somatic mutations in circulating tumor DNA (ctDNA) in serial samples correlate with the number of days of the progression-free period and with the overall survival.

Enrollment: 25 estimated patients

Sex: Female

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Metastatic breast cancer before the start of chemotherapeutic treatment

Exclusion criteria

• Patients with incomplete clinical records