Genetic Origin of Lipid Disorders

University of Oslo

Status: Unknown

Conditions: Lipid Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT00277121

02/4746 (SHdir)

10163 (NSD)

S-03150 (REK)

Details and patient eligibility

About

Several lipid disorders are without known genetic origin. The scope of this project is to sequence genes superior involved in lipid and carbohydrate metabolism in patients with severe lipid disorders. The resulting mutations will be tested in suitable in vitro systems to detect their part in development of the specific disease.

Full description

See "brief summary" above.

Sex: All

Ages: 18 to 54 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• proven written informed consent prior to recruitment
• male or female
• 18-55 years old
• patients with severe lipid disorders
• fasting plasma cholesterol, triglyceride or glucose, blood pressure or waist circumference/BMI out of normal range

Exclusion criteria