Genetic Polymorphism and Parkinson's Disease in Taiwanese

Changhua Christian Medical Foundation

Status: Completed

Conditions: Parkinson's Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01996878

CCH060105

Details and patient eligibility

About

To observe and analyze the correlation between Single Nucleotide polymorphisms (SNPs) and the incidence of Parkinson's disease in Taiwanese.

Enrollment: 334 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Parkinson's disease (case subjects are diagnosed by the presence of at least three of the five following primary signs: rest tremor, bradykinesia, rigidity, impaired postural refluxes, and the presence of a sustained L-dopa response.)
• Healthy volunteers without Parkinson's disease

Exclusion criteria

• Cases showing atypical features, including multiple system atrophy and progressive supranuclear gaze palsy, or secondary causes of Parkinsonism, such as neuroleptic drugs, infection, tumor, previous cerebrovascular accident and known toxins

Trial design

334 participants in 2 patient groups

Case (Parkinson's disease patients)

Description:

Clinical diagnosis of Parkinson's disease (cases are diagnosed by the presence of at least three of the five following primary signs: rest tremor, bradykinesia, rigidity, impaired postural refluxes, and the presence of a sustained L-dopa response.)

Control (Healthy volunteers)

Description:

Healthy volunteers without Parkinson's disease