Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD

University Hospital Center (CHU) Dijon Bourgogne

Status: Completed

Conditions: Glaucoma

Treatments: Biological: assessing the blood level of cholesterol 24 S hydroxylase; Biological: Assessing the blood level of cholesterol 24 S hydroxylase; Biological: Assessing the blood level of cholesterol 24 S Hydroxylase

Study type: Interventional

Funder types: Other

Identifiers

NCT00629044

PHRC IR 2006

Details and patient eligibility

About

The aim of this study is to assess the implicitement of the cholesterol 24 S hydroxylase gene and the 24 S hydroxycholesterol in glaucoma and in age related macular degeneration.

Enrollment: 320 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient with Glaucoma
• Patient with AMD
• Healthy patient

Exclusion criteria

• All patients who use any treatment in order to maintain in normal value their blood cholesterol

Trial design

Primary purpose: Screening

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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320 participants in 3 patient groups

G

Active Comparator group

Treatment:

Biological: Assessing the blood level of cholesterol 24 S Hydroxylase

AMD

Active Comparator group

Treatment:

Biological: Assessing the blood level of cholesterol 24 S hydroxylase

Healthy subjects

Active Comparator group

Treatment:

Biological: assessing the blood level of cholesterol 24 S hydroxylase