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Genetic Study of Lupus Patients and Their Families

O

Oklahoma Medical Research Foundation

Status

Completed

Conditions

Systemic Lupus Erythematosus

Study type

Observational

Funder types

Other
NIH

Identifiers

NCT00235378
R01AR043274 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to perform genetic testing in and to collect information from families affected by lupus in order to identify the genetic factors associated with systemic lupus erythematosus (SLE).

Full description

Little is known about the genetic factors that predispose people to developing SLE. Genes in patients with SLE may provide clues about SLE's pathogenesis. This study will compare genes from SLE patients, their unaffected family members, and control participants. Travel to the study site is not required.

In this study, blood samples will be collected from people diagnosed with SLE, their unaffected family members, and condition-matched controls. Participants will be asked questions about their health and will provide a small blood sample. Participants will also be asked to provide written permission for release of medical information, so that their disease status can be verified through medical record review or through consultation with their doctors. Study personnel may contact participants in the future for follow-up questions and additional blood draws, if the participant agrees.

Enrollment

2,356 patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Diagnosis of SLE OR a family member of participant diagnosed with SLE

Exclusion criteria

  • Pregnancy or breastfeeding

Trial design

2,356 participants in 3 patient groups

1
Description:
SLE patients
2
Description:
Unaffected family members of SLE patients
3
Description:
Control participants

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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