Genetic Susceptibility to Radiation Induced Thyroid Cancer

Institut National de la Santé Et de la Recherche Médicale, France

Status: Completed

Conditions: Genetic Susceptibility; Thyroid Neoplasms; Radiation Exposure

Study type: Observational

Funder types: Other

Identifiers

NCT04139096

C 17-69

Details and patient eligibility

About

Case control on thyroid cancer occuring in a cohort of 7300 subjects treated during their childhood, mostly by radiotherapy, for a skin Angioma at Gustave Roussy, Villejuif France between 1947 and 1973.

This case control study, which is included in a larger european project, aims to investigate the DNA variant interacting with the risk of radiation induced thyroid cancer after irradiation.

The sutdy is planed to include about 30 cases and 30 controls. Matching criteria are date of birth, gender, and age at irradiation.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Diganosis of thyroid cancer during the followup or selected as a control matched on gender, date of birth and age at skin hemangioma diagnosis.

Exclusion criteria

No available adress Refusal