Genetics and Mechanisms of Rheumatoid Arthritis (RASGENAS)

Slovak Academy of Sciences

Status: Completed

Conditions: Genetic Association Studies; Leukocytes, Mononuclear; Rheumatoid Arthritis

Study type: Observational

Funder types: Other

Identifiers

NCT01788098

ATMOS N00024 (Other Grant/Funding Number)

RASGENAS

Details and patient eligibility

About

The study is aimed at revealing genetic background in rheumatoid arthritis (RA). For that purpose samples of DNA will be collected from 500 RA patients and similar number of controls from whole Slovakia. Variations in several genes associated with RA will be evaluated. The second aim is to assess functional changes in immune cells from selected patients and their evaluation together with genetic background. The project has observational character without any intention to change the treatment of RA patients.

Enrollment: 790 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• rheumatoid arthritis or healthy

Exclusion Criteria:

Trial design

790 participants in 2 patient groups

Rheumatoid Arthritis

Description:

Patients with rheumatoid arthritis

Healthy controls

Description:

Healthy control subjects