Genetics of Cardiovascular and Neuromuscular Disease

The University of Chicago

Status: Enrolling

Conditions: Cardiomyopathy; Arrhythmia; Muscular Dystrophy

Treatments: Procedure: Blood draw (genetic testing)

Study type: Observational

Funder types: Other

Identifiers

NCT00138931

8249

Details and patient eligibility

About

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Enrollment: 2,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.

Exclusion criteria

• Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.