Genicular Nerve Block for Knee Pain in the ED

University of Pennsylvania

Status: Enrolling

Conditions: Knee Pain

Treatments: Other: Standard of Care; Procedure: Genicular nerve block with bupivacaine and corticosteroids

Study type: Interventional

Funder types: Other

Identifiers

NCT07158736

IRB Protocol #858259

Details and patient eligibility

About

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

Enrollment: 34 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Atraumatic knee pain
• >17 years age
• X-ray of the knee obtained in the ED
• Initial pain score (numeric rating scale) 5-10

Exclusion criteria

• Fracture or dislocation on x-ray
• large knee joint effusion identified on x-ray
• allergy or contraindication to local anesthetics
• History of local anesthetic systemic toxicity after receiving local anesthetics
• Pregnancy
• Incarcerated
• History of knee replacement of affected knee
• Concern for septic joint
• Overlying cellulitis
• Hemodynamic instability
• Altered mental status or inability to consent for procedure.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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34 participants in 2 patient groups

Genicular Nerve Block

Experimental group

Description:

This arm of patients (17 total) will receive the genicular nerve block for their knee pain.

Treatment:

Procedure: Genicular nerve block with bupivacaine and corticosteroids

Standard of Care

Active Comparator group

Description:

This arm of patients (17 total) will receive standard of care analgesia for their knee pain

Treatment:

Other: Standard of Care