Genicular Nerve Block Versus Its Combination With Infiltration Between Popliteal Artery and Capsule of Posterior Knee

Zagazig University

Status: Enrolling

Conditions: Postoperative Pain

Treatments: Procedure: GNB plus standard analgesia; Procedure: GNB plus IPACK block plus standard analgesia; Drug: standard analgesia (paracetamol and meloxicam)

Study type: Interventional

Funder types: Other

Identifiers

NCT05672784

9577/19-9-2022

Details and patient eligibility

About

Comparison of the analgesic and physical recovery effect of genicular nerve block (GNB) alone and (GNB + infiltration between popliteal artery and posterior capsule of the knee (IPACK) in patients undergoing total knee replacement

Full description

Comparison of preemptive analgesia of (GNB) with (GNB+ IPACK) on postoperative pain control and recovery of knee physical activity in patient undergoing total knee replacement.

Enrollment: 63 estimated patients

Sex: All

Ages: 21 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria:

• Adult patients aged between 21 to 60 years
• undergoing primary unilateral elective total knee arthroplasty under spinal anesthesia
• Having informed consents
• patients with physical status ASA I & II
• both genders
• body mass index less than 40 kg/m2.

Exclusion criteria

• patients with Peripheral vascular disease
• patients with history of allergy to local anesthesia or opioid analgesia,
• those on anti-platelet, anticoagulant or B blocker drugs
• Patients with acute decompensated heart failure
• Patients with hypertension
• Patients with heart block
• Patients with coronary disease
• Patients with bronchial asthma
• Patients with bleeding disorders
• Patients with compromised renal or hepatic function
• pregnant female.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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63 participants in 3 patient groups

C group

Active Comparator group

Description:

the patients will take standard analgesia ( meloxicam (15 mg) once a day + paracetamol 1gm /3 times a day). ,with no nerve block

Treatment:

Drug: standard analgesia (paracetamol and meloxicam)

G group

Active Comparator group

Description:

the patients will take standard analgesia plus GNB

Treatment:

Drug: standard analgesia (paracetamol and meloxicam)

Procedure: GNB plus standard analgesia

GI group

Active Comparator group

Description:

the patients will take standard analgesia plus GNB plus IPACK

Treatment:

Drug: standard analgesia (paracetamol and meloxicam)

Procedure: GNB plus IPACK block plus standard analgesia