Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm

State University of New York - Upstate Medical University

Status: Terminated

Conditions: Subarachnoid Hemorrhage; Arteriovenous Malformations; Intracranial Aneurysm

Study type: Observational

Funder types: Other

Identifiers

NCT01801488

IRB#238810

Details and patient eligibility

About

Test single nucleotide polymorphisms (SNP's) in ruptured and unruptured aneurysm tissue to identify a genetic difference between the two types of aneurysms; and to test SNP's in arteriovenous malformation tissue to identify a genetic link.

Enrollment: 5 patients

Sex: All

Ages: 18 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• All adult patients between the ages of 18 and 89 that are having open surgical resection of an AVM or clipping of an aneurysm will be included

Exclusion Criteria:

Trial design

5 participants in 3 patient groups

AVM Patients

Description:

Patients receiving surgical intervention for an intracranial arterial-venous malformation.

Ruptured Aneurysm

Description:

Patients receiving surgical intervention for a ruptured intracranial aneurysm.

Unruptured Aneurysm

Description:

Patients receiving surgical intervention for an unruptured intracranial aneurysm.