Genome-wide Association Study of Development of Collateral Circulation for Patients With Coronary or Peripheral Artery Disease (GWAScollateral)

Jung-min Ahn

Status: Enrolling

Conditions: Peripheral Arterial Disease; Coronary Disease; Collateral Circulation, Any Site

Treatments: Diagnostic Test: Blood samples

Study type: Observational

Funder types: Other

Identifiers

NCT05043948

GWAS_collateral

Details and patient eligibility

About

The purpose of this study is to evaluate the genome-wide association for the development of collateral circulation for patients with coronary or peripheral artery disease and to develop the molecular genetic treatment model based on genome-wide association data.

Enrollment: 400 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age more than 20
• Chronic total occlusive lesion from the coronary or peripheral angiogram

Exclusion criteria

• Renal dysfunction
• Hepatic dysfunction
• Thrombocythemia or thrombocythemia
• Planned major surgery in 1 year
• History of gastrointestinal haemorrhage
• Malignant tumor

Trial design

400 participants in 4 patient groups

Coronary Artery Disease_collateral flow grade 2

Treatment:

Diagnostic Test: Blood samples

Coronary Artery Disease_collateral flow grade 0

Treatment:

Diagnostic Test: Blood samples

Peripheral Artery Disease_collateral flow grade 2

Treatment:

Diagnostic Test: Blood samples

Peripheral Artery Disease_collateral flow grade 0

Treatment:

Diagnostic Test: Blood samples