Genotype and Phenotype in Early Onset Breast Cancer in Young Women on the Two Shores of the Mediterranean Sea (MediSein)

University Hospital Center (CHU)

Status: Terminated

Conditions: Breast Cancer

Treatments: Genetic: Genetic analysis

Study type: Observational

Funder types: Other

Identifiers

NCT02541188

UF 9428

Details and patient eligibility

About

Breast cancer are common on mediterranean basin. Epidemiological data suggest that breast cancer in young women (< 40years old) is more aggressive in the Maghreb countries comparatively to western countries. This aggressiveness could be associated with phenotypic and genotypic differences between this two populations.

Full description

The object of this study is to compare the genotypic and phenotypic differences between south and north shore of the mediterranean sea.

Enrollment: 460 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient have or have had a breast cancer diagnosed before 40 years old
• Breast cancer proven by histology
• BRCA1/2 analysis proposed, realized, ongoing
• Women >18 years old
• Patient with insurance
• Patient informed and no-opposed

Exclusion criteria

• Patient have or have had a breast cancer diagnosed after 40 years old
• Patient requiring tutorship or guardianship
• Adult patient protected by law

Trial design

460 participants in 2 patient groups

breast cancer in young women is in the Maghreb

Description:

breast cancer in young women (\< 40years old) is in the Maghreb

Treatment:

Genetic: Genetic analysis

Breast cancer in young women in the western countries

Description:

Breast cancer in young women (\< 40years old) in the western countries

Treatment:

Genetic: Genetic analysis