Genotype-phenotype Correlation and Pathogenic Mechanism in Hereditary Ataxia

Zhejiang University

Status

Enrolling

Conditions

Hereditary Ataxia

Study type

Observational

Funder types

Other

Identifiers

NCT05160870

Wulab-sNfL in HA

Details and patient eligibility

About

The investigators aimed to find appropriate biomarkers such as serum neurofilament light chain in reflecting disease severity in hereditary ataxia from a large cohort during long-term follow-up. The disease severity is indicated by clinical scales and brain MRI tests.

Enrollment

500 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria