Genotyping FcɣRs Genes of HIV-1 Patients "Progressor": Correlation With the Changing Profile of the Infection

University Hospital, Strasbourg, France

Status: Unknown

Conditions: HIV Infection

Study type: Observational

Funder types: Other

Identifiers

NCT03130296

6493

Details and patient eligibility

About

This non-interventional study aims to determine whether there is a correlation between the Fc receptor polymorphism (FcR) and the course of the disease following HIV infection.

Enrollment: 230 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged 18 or older,
• Patient affiliated to a social security scheme,
• Informed consent dated and signed by the investigating physician the patient,
• Patients infected with HIV-1 having progressed in clinical (stage C) or biologically (CD4 nadir <350 / mm3 and viral load> 10,000 copies / ml)

Exclusion criteria

• Impossibility of giving the subject informed information (subject in an emergency situation, difficulty in understanding the subject, ...)
• Subject under safeguard of justice,
• Subject under tutelage or under curatorship,