GER Poses a Potential Risk for Late Complications of BPD

China Medical University

Status: Completed

Conditions: Gastroesophageal Reflux; Bronchopulmonary Dysplasia

Study type: Observational

Funder types: Other

Identifiers

NCT03014453

A333-1

Details and patient eligibility

About

Bronchopulmonary dysplasia (BPD) is a common condition in the low birth weight infants. Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late complications left such as the frequent respiratory symptoms, a slower weight gain and even sudden death. These late complications have made so much trouble to the healthcare of BPD infants. How to find the risk factors and to reduce the prevalence of these late symptoms becomes necessary. In this study, a cohort of BPD infants was observed with the late complications obtained by a monthly followed up for 18 months after discharge, the prevalence and risk factors of the late complications of BPD were analyzed by logistic regression. As one of the risk factors, GER was verified whether to play a critical role in these late complications.

Enrollment: 187 patients

Sex: All

Ages: Under 32 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• the extremely premature infants with bronchopulmonary dysplasia

Exclusion criteria

• other congenital malformations such as gastrointestinal and or neurogenic disease

Trial design