Geriatric and Oncologic Assessment Before Treatment (GOAT)

Odense University Hospital

Status: Unknown

Conditions: Cancer

Treatments: Other: G8 screening; Other: Geriatric assessment

Study type: Interventional

Funder types: Other

Identifiers

NCT02671994

GOAT (Other Identifier)

Details and patient eligibility

About

In a randomized controlled trial, the investigators wish to investigate, if oncologic treatment decision based on G8 screening followed by geriatric assessment and subsequent MDT, if needed, in older frail patients with gynaecologic and urologic cancer is superior to standard assessment (PS and clinical assessment) in oncologic treatment decision.

Enrollment: 114 patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically verified gynaecologic cancer (ovarian, uterine, or cervical cancer) or urologic cancer (prostate, bladder, or kidney cancer).
• Suited for first line medical oncologic treatment with chemotherapy and/or targeted therapy.
• Age ≥ 70 years.
• Understands, speaks, and writes Danish.
• Signed informed consent.

Exclusion criteria

• Previous cancer diagnosis except for carcinoma in situ of the cervix or skin cancer other than malignant melanoma.
• Previous chemotherapy and/or targeted therapy for current cancer diagnosis.
• Previous radiation therapy or concomitant radiotherapy for current cancer diagnosis.
• Surgery within the last 4 weeks.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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114 participants in 2 patient groups

A (experimental group)

Experimental group

Description:

Oncologic treatment decision based on G8 screening followed by geriatric assessment and subsequent MDT, if needed, in addition to standard assessment (ECOG Performance Status + clinical assessment).

Treatment:

Other: Geriatric assessment

Other: G8 screening

B (control group)

No Intervention group

Description:

Oncologic treatment decision based on standard assessment (ECOG Performance Status + clinical assessment).