Geriatric Assessments in Elderly Diffuse Large B-cell Lymphoma

Chonbuk National University

Status: Completed

Conditions: Lymphoma, Large B-cell, Diffuse

Study type: Observational

Funder types: Other

Identifiers

NCT02555267

GERIAD

Details and patient eligibility

About

This study investigate the impact of comprehensive geriatric assessments using activity of daily living (ADL), instrumental activity of daily living (IADL), and Charlson's comorbidity index (CCI) on survival and toxicities in Korean patients with diffuse large B-cell lymphoma (DLBCL) treated with R-CHOP.

Enrollment: 148 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with newly diagnosed CD20+ DLBCL
• 65 years old or over
• Scheduled to receive R-CHOP chemotherapy
• Informed consent

Exclusion criteria

• Other histology than CD20+ DLBCL
• Primary central nervous system DLBCL
• Patients with a diagnosis of cancer (other than basal or squamous cell carcinoma of the skin, cervical carcinoma in situ, well differentiated thyroid cancer [papillary or follicular thyroid cancer]) within 3 years before the study entry or with any treatment for cancer within 3 years before entry
• Consent withdrawal

Trial design

148 participants in 1 patient group

Elderly patients with DLBCL

Description:

Elderly patients (age>=65 years) with DLBCL treated with R-CHOP chemotherapy