Geriatric Determinants of General Repercussion of Radiotherapy for Patient Over 75 Years With Prostate Cancer (PROGERAD)

Institut Cancerologie de l'Ouest

Status: Completed

Conditions: Prostate Cancer

Treatments: Other: geriatric assessment and quality of life; Radiation: Radiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02876237

2014-A00300-47 (Other Identifier)

ICO-A-2014-04

Details and patient eligibility

About

The investigators propose to carry out a prospective analysis of physical impact, psychological, cognitive and social of radiotherapy in all patients over 75 years bearer of localized prostate cancer with an indication of curative radiotherapy. This standardized geriatric assessment will collect social information, functional, sensory, cognitive, emotional, motor, nutritional, and medical related to comorbidities . The quality of life of patients will be evaluated by the QLQ C30 (Quality of Life Questionnaire) European Organisation for Research and Treatment of Cancer (EORTC) before starting treatment, at the end of radiotherapy (2 months) and at 6 months. This short follow-up period seems appropriate in this elderly population and will allow an answer within 2 years to the problem raised in clinical practice.

Enrollment: 230 patients

Sex: Male

Ages: 75+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Man with a histologically proven prostate cancer
2. Indication of a curative intent radiotherapy
3. Age ≥ 75 years
4. Patient who signed an informed consent

Exclusion criteria

1. Patient with metastatic prostate cancer
2. Patient unable to submit to monitoring of the protocol for social, geographical or family reasons
3. A person who is not affiliated to a social security scheme or of such a scheme
4. Patient under trusteeship

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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230 participants in 1 patient group

geriatric assessment and quality of life

Experimental group

Description:

Included patient must have a geriatric assessment before radiotherapy and 6 months later. Patient must complete quality of life questionnaire before radiotherapy then 2 and 6 months later.

Treatment:

Radiation: Radiotherapy

Other: geriatric assessment and quality of life