German Inclisiran Network: Retrospective Registry of Patients Being Treated With the siRNA Inclisiran in Germany (GIN)

Jena University Hospital

Status: Enrolling

Conditions: Hypercholesterolemia

Study type: Observational

Funder types: Other

Identifiers

NCT05438069

2021-2429

Details and patient eligibility

About

The German Inclisiran Network is a registry of patients with hypercholesterinemia on treatment with the siRNA inclisiran in Germany

Full description

The aim of this retrospective, multi-center analysis is to use individual patient data to determine the extent of the variability in LDL-C reduction in response to inclisiran administration in a real-world setting.

Enrollment: 500 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with elevated LDL-C levels (hypercholesterolemia) on stable lipid-lowering drugs for at least one month prior to the application of the siRNA Inclisiran
• patients 18 years and older

Exclusion criteria

• patients who do not qualify for treatment with the siRNA inclisiran according to the G-BA (Gemeinsamer Bundesausschuß) in Germany.

Trial design

500 participants in 1 patient group

Patients with elevated LDL-cholesterol (hypercholesterolemia)

Description:

Application of si RNA Inclisiran to reduce serum LDL-cholesterol levels.