Gestational Diabetes Mellitus and Implications for Cardiovascular Disease Risk

Mass General Brigham

Status: Unknown

Conditions: Gestational Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT00550979

2007P001406

Details and patient eligibility

About

The purpose of this research study is to look at whether there are differences in blood vessel function, risk for developing diabetes (high blood sugar), lipid (blood fat) levels, and levels of other blood markers in women who have had a pregnancy complicated by diabetes as compared with women who have had a normal pregnancy.

Enrollment: 96 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy women of self-identified African descent (black) and European (white) ancestry
• 18-40 years of age
• Regular menstrual cycles
• 5 or less years postpartum
• Have either a normal or a GDM index pregnancy history
• Are in good health free of thyroid, cardiac, or renal disease

Exclusion criteria

• If you are pregnant
• If you are lactating

Trial design

96 participants in 4 patient groups

1

Description:

Black women with history of pregnancy/ies complicated by gestational diabetes mellitus

2

Description:

Black women with history of normal, uncomplicated pregnancy/ies

3

Description:

White women with a history of pregnancy/ies complicated by gestational diabetes.

4

Description:

White women with a history of normal, uncomplicated pregnancy/ies.