Gestational Diabetes Mother-infant Cohort

Gansu Provincial Maternal and Child Health Care Hospital

Status: Enrolling

Conditions: Gestational Diabetes Mellitus in Pregnancy; Cognitive Impairment; Cohort Study

Treatments: Behavioral: Acquired nurturing environment

Study type: Observational

Funder types: Other

Identifiers

NCT06021691

NCRCCHD-2022-GP-17

Details and patient eligibility

About

The bi-directional dynamic cohort study is to learn about the effects of prenatal exposure to high blood glucose levels and postnatal nurturing environment factors on delayed language development in children. The study investigated the results of blood glucose screening during pregnancy for the children's mothers, and followed up on the blood glucose management effectiveness of pregnant women with abnormal blood glucose levels before delivery. Participants will be also surveyed the "S-S method for language development assessment, "gsell Scale", and "0-6 year-old family nurturing environment evaluation scale" to evaluate the language development and family nurturing environment.

Full description

Glucose management during pregnancy and the postnatal nurturing environment are keys to early detection and early intervention of language delay, which is important to reduce abnormal language development in children. In this study, mothers diagnosed with gestational diabetes mellitus in the department of hospital and offspring were used as participants. The investigators take a follow-up visit to participants' offspring using the S-S method of language development assessment, gsell Infant and Toddler Development Scale, and 0-6 years old family parenting environment evaluation scale. The bi-directional dynamic cohort study is to learn about the effects of prenatal exposure to high blood glucose levels and postnatal nurturing environment factors on delayed language development in children.

Enrollment: 600 estimated patients

Sex: All

Ages: 1 to 3 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Children 1.5-2.5 years old with no serious underlying diseases and no hearing impairment.

Exclusion criteria

• diagnosed hearing impairment, organic dysarthria, oral disease; (ii) cerebral palsy;
• neurological and hereditary metabolic diseases; (iv) deaf father/mother.

Trial design

600 participants in 2 patient groups

Gestational diabetes offspring cohort

Description:

The Gestational diabetes(GDM) offspring cohort is to learn about language development assessment in 2-year-old children and causal association with their mother who diagnosed GDM

Treatment:

Behavioral: Acquired nurturing environment

Healthy maternal offspring cohort

Description:

Healthy maternal offspring cohort is to learn about language development assessment in 2-year-old children and causal association with their health mother

Treatment:

Behavioral: Acquired nurturing environment