Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults

Universidade Federal Fluminense

Status: Completed

Conditions: Age Problem

Treatments: Procedure: 0.12% chlorhexidine

Study type: Interventional

Funder types: Other

Identifiers

NCT04658225

CAAE: 69912817.0.0000.5626.

Details and patient eligibility

About

The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.

Full description

Thirty patients with gingivitis ages 18 to 30 year with a probing depth of at most 3 mm and at least 20 teeth will be selected and evaluate at baseline and after 4 weeks.

Enrollment: 30 patients

Sex: All

Ages: 30 to 30 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Presence of gingivitis
• Probing depth (PD) with maximum 3 mm
• Minimum of 20 teeth
• Age between 18 and 30 years old

Exclusion criteria

• Patients with periodontal disease (PD ≥ 4mm with clinical attachment loss)
• Diabetes
• Osteoporosis
• Pregnant or lactating females
• Smokers
• Users of immune suppressive medication
• Phenytoin or cyclosporine
• Calcium channel blockers
• Antibiotics
• Nonsteroidal anti-inflammatory drugs
• HIV+ or AIDS

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups, including a placebo group

Solution 1

Active Comparator group

Description:

0.12% chlorhexidine

Treatment:

Procedure: 0.12% chlorhexidine

Solution 2

Placebo Comparator group

Description:

Saline solution

Treatment:

Procedure: 0.12% chlorhexidine