Ginseng HRG80 in Stress and Fatigue

EuroPharma

Status and phase: Completed; Phase 2; Phase 1

Conditions: Psychological Stress

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Panax ginseng; Dietary Supplement: HRG80 Panax ginseng

Study type: Interventional

Funder types: Industry; Other

Identifiers

NCT03947554

EP-1005

Details and patient eligibility

About

This study evaluates the effects of a specific herbal preparation of Panax ginseng in preventing symptoms of stress in healthy individuals.

Full description

HRG80 is an herbal preparation of Panax ginseng with a higher concentration of bioavailable ginsenosides than typical Korean ginseng. This study will test whether HRG80 is effective at preventing symptoms of stress, such as fatigue, impaired memory, difficulty in concentration, attention deficit, restlessness, and irritation related to daily work situations of healthy individuals in comparison to placebo and a standard Pananx ginseng with a lower concentration of ginsenosides.

Enrollment: 50 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Individuals experiencing at least one symptom of stress and fatigue during 8 hours of mental work with a computer.
• Men and women ages 18-65 (all races and ethnicities)
• Able to understand and participate in an 11-week study

Exclusion criteria

• Taking medicine or dietary supplements which may have potential effects on cognitive function
• Consuming more than 1 cup of coffee daily (in the morning).

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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50 participants in 3 patient groups, including a placebo group

HRG80 Panax ginseng

Experimental group

Description:

Panax ginseng standardized to 63.4 mg of total ginsenosides taken orally once daily in the morning after a meal.

Treatment:

Dietary Supplement: HRG80 Panax ginseng

Panax ginseng

Active Comparator group

Description:

Panax ginseng standardized to 19.6 mg of total ginsenosides taken orally once daily in the morning after a meal.

Treatment:

Dietary Supplement: Panax ginseng

Placebo

Placebo Comparator group

Description:

Placebo capsule containing brown sugar and rice flour, taken orally once daily in the morning after a meal.

Treatment:

Dietary Supplement: Placebo